Wood is one of the most versatile and at the same time most important renewable raw materials. Wood preservatives protect the material from damage caused by moisture, insects and UV rays. Many commercially available wood preservatives contain chemicals that are harmful to health and the environment. These active ingredients are regulated by the Biocide Regulation and many of the registered substances will lose their registration in the foreseeable future due to their human and/or environmental toxicity. Sustainable, biological and, above all, non-toxic active substances will therefore become irreplaceable in the future.
The aim of the presented research work is to develop a biotechnologically produced phytoextract for use as a hydrophobic wood preservative and preservative with fungicidal effect from plant in vitro sage cell cultures on an industrial scale. Only bio-based and toxicologically safe active ingredients are to be used.
Extracts or ingredients of plants are traditionally produced from agricultural material. Depending on various influencing factors such as location and production period, the extracts obtained differ in quality and quantity. For a continuous, sustainable production of plant ingredients, the use of biotechnological processes based on plant in vitro cultures is required. The cultivation of plant cells in a closed bioreactor system ensures the sustainable production of plant secondary metabolites with consistent quality and quantity. To achieve adequate productivities with plant cell suspension cultures, elicitation is a widely used strategy. The targeted use of so-called elicitors in plant cell cultures stimulates plant defense mechanisms, which can be used to increase drug yields.
The Federal Ministry of Education and Research (BMBF) financially supports this work, the project ID is 031B0929A.